The CHRISTMAS, the 'Cys-His-Arg-Ile-Ser-Thr' (C-H-R-I-S-T) amino acid sequence and the SARS-CoV-2 Spike.
Merry Christmas to everyone, also to those who celebrate, enjoy, believe and remember traditions. This post was written on December 24-th, the Christmas Eve, the day of the year, many believe, including myself, Jesus was born.
Updates:
12/25/2023 The bioinformatics analysis presented here will be continued, so checking occasionally for those who are interested would make sense. The post might become huge… Thank you for reading and not-unsubscribing;))
1/1/2024: HAPPY NEW YEAR WITH NEW HOPES for more JUSTICE, PEACE and LOVE and appreciation for our Creator, on this planet. An incredible scientist will REVOLUTIONIZE the world with new truths, FACTS: https://expose-news.com/2024/01/01/let-a-scientist-speak-presentation-goes-viral-because-its-true/ and music, can support our battled souls on a different level:
There is only one word which relates to the night today and that is the word CHRIST.
It means a lot to many, special birth, love, wonders, devotion, forgiveness, peace, special death, but also the highest power.
This short post will relate molecular biology and religion, via this one word CHRIST. For people who read bible the meaning of WORD is very important. In todays world where religion is attacked on every level, where values are destroyed, and creation is being overwritten via GENETICS, one has to realize the level of hidden complexity by those who have the power to know and to decide what others know, and become. As usual, all will be based on bioinformatics, assumed as a known tool for the reader.
Natural proteins contain 20 amino acids described by a single letter code covering the entire alphabet except for the letters : B, J, O, U, Z, X. These missing letters in protein codes already exclude the existence of the short pentapeptide, like for example ‘J-E-S-U-S’. As a side note, there is one special artificial amino acid ‘hybrid’ called glyphosate. It represents a mix of glycine (the human inhibiting neurotransmitter) and a phosphono-group, together called N-phosphonomethylglycine. Wi-ki calls it broad-spectrum systemic herbicide and crop desiccant… And there are more, but will be left out for now.
One can start with opening the NIH BLAST page at https://blast.ncbi.nlm.nih.gov/Blast.cg (with ‘PROTEIN’ analysis option) and type into the search window the fasta code ‘CHRIST’ which is equivalent to ‘Cys-His-Arg-Ile-Ser-Thr’=’Cysteine-Histidine-aRginine-Isoleucine-Serine-Threonine’ or the string of letters ‘C-H-R-I-S-T’. Now search for ‘Reference Proteins’ with blastp algorithm and just hit BLAST button. Enough to choose the default first 100 hits, one can go much higher and deepen the analysis.
If the amino acid sequence ‘CHRIST’ (from now on it will be called ‘CHRIST section’ because in this search it represents a short peptide as defined by molecular biologists, an amino acid sequence) had no meaning in all the found proteins, their relation for example to SARS-CoV-2 Spike (its amino acid sequence is at https://www.ncbi.nlm.nih.gov/protein/YP_009724390.1) should be zero, but it is not.
The result shows proteins with 100% hit for the word ‘CHRIST’ from all possible organisms sorted after amino acids length, i.e. molecular weight. Let’s take the first one, non-ribosomal peptide synthetase with the NIH code WP_052438536.1, and compare it with the SARS-CoV-2 Spike (BLAST search with 2 entries in which Spike will be the line with query in all the examples below), one gets 78% coverage with 47% identities, using special parameters. Here just 3 hits, chosen according their importance in Spike features, among countless others:
Query 663 DIPIGAGICASYQTQTNSPRRAR 685 Spike's FURIN Site
+ P AG+ A ++ T + ++AR
Sbjct 6346 EAPTVAGVAARIESLTTTKKKAR 6368 WP_052438536.1
Query 460 NLKPFERDISTEIYQAGST 478 Spike's ACE2 binding site
+L P RD+S+ Y A +T
Sbjct 3323 SLAPLARDVSAA-YAARTT 3340 WP_052438536.1
Query 704 TMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDST 747
+ S +++ ++ +P+ + E+ ++T D T + GD T
Sbjct 2581 DVAECHRISTEWNDTAVDLPA----ATLPELFAAQAARTP-DATALVFGDET 2619
Note the last line with the CHRIST sequence, Spike doesn’t have it. Let’s take the IgGFc-binding protein XP_030268704.1, which comes up for many organisms in this search. The first is the section containing the ‘ALLAG-TITS-G-WTF-GAGAA
‘, it was mentioned many times in my posts, here it really looks like it was added into Spike with the conserved ‘TSGW’ tetrapeptide… Spike sequence is in query line, IgGFc sequence in Sbjct line:
Query 844 IAARDLICAQKFNG-LTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQM
+ ++D A NG L+ LP +L + I Y TSGW A ++ F +++
Sbjct 409 VISKDNPGAVVINGELSNLPMMLNNNTIHLY---------TSGWF----AVIETDFGVKL
Query 1034 LGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREG
+GQS D C H S Q A VV ++T P + C+ + G
Sbjct 1067 VGQSIITDDC----HRISTCQ-ASGVVVSQNMTCDPNESCLVKNGVMGCYIQQCFLDSNG
The last line with the divided CHRIST sequence is not present in Spike, except for the C, H and S residues. Is IgG-Fc somewhat related with covid19? Just one citation^1 showing how important it is, with no further analysis. The next one, transmembrane channel-like protein 3 XP_049638825.1, with over 30% identities:
Query 1 MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNS 31 Spike
M F+V+ L++ Q T+R ++PP + S
Sbjct 154 MGAFVVIPELIAGQPFGSTARKRVPPEHVAS 184 XP_049638825.1
Query 1082 CHDGKAHFPREGVFVSNGTH 1101 Spike
CH + P+ + TH
Sbjct 746 CHRISTCSPKGRCSRAPSTH 765 XP_049638825.1
The word ‘CHRIST’ disappears in Spike, except for the first CH and last T residues. despite of many similar sections. Try to run similarities with the transmembrane channel-like protein 3 and nsp3 from SARS-CoV-2, 67% sequence coverage and ~40% identities including section showing their direct electrostatic relationship:
Query 842 EEEGEEE 848
EEE EE+
Sbjct 154 EEEQEED 160
Next protein, XP_007803561.1, P-type cation-transporting ATPase, this time the ‘CHRIST’ section in the first hit is not conserved, but other fragments are, the special perverse one, even for this totally different protein, comes up, again:
Query 91 YFASTEKSNIIRGWIFGTTLDSK 113 Spike2020
Y A T R G +LD +
Sbjct 141 YIAKTTGFTCHRISTHGQSLDIR 163 XP_007803561.1
Query 880 GTITSG-------------WTFGAGAALQI------PFAMQMAYRFNGIGVTQNVLYENQ
GT+T G + A AL + P + +A GV + VL EN
Sbjct 581 GTLTKGELSVLAEDHFSESQSVAASIALGLTMNSKHPVSAALAAHLQARGV-EPVLIENM
Cation transporting ATP-ase is involved in binding Mg, a process affected by SARS-CoV-2^2.
Next protein eukaryotic translation initiation factor 2-alpha (code XP_048641134.1), almost 38% identical with Spike:
Query 452 LYRLFRKSNLKPF-ERDISTE 471 Spike ACE2 binding domain
++ F KPF E DI +
Sbjct 277 IFAEFTSEKEKPFGECDIENQ 297 TIF2A
Query 485 GFNCYFPLQ-SYGFQP 489 SPIKE
G C S P
Sbjct 397 GHYCHRISTLSGQVCP 401 XP_048641134.1 = TIF2A
The ‘CHRIST’ section is gone again, except fot the first Cys residue.
Next protein reverse transcriptase/maturase family WP_087017951.1 with 71% identities(!!!) over 50% sequence coverage:
Query 446 GGNYNYLYRLFRKSNLKP 463 Spike
GG + L RKS P
Sbjct 252 GGICHRISTLHRKSKNNP 269 WP_087017951.1 reverse transcriptase
Query 668 AGICASYQT-QTNSPRRARSVASQSIIAYTMSLGAEN---SVAYSNNS 711 FURINsite
GIC T S S + IA + L + V NN
Sbjct 252 GGICHRISTLHRKSKNNPDSPDREKWIAEEVELKRQRVKIPVYQDNNK 299
Query 1246 GCCSCGSCCKFDEDDSEPVL 1265 Spike
G C C DSEPV+
Sbjct 541 GICELCGC------DSEPVV 554 WP_087017951.1
Query 1098 NGTHWFV 1104 Spike
NGT+WF+
Sbjct 150 NGTKWFI 156 WP_087017951.1
In the above example 2 different Spike sections match the ‘CHRIST’ section from the reverse transcriptase. The high homology between Spike and reverse transcriptase is troubling, and like above, it does not contain the ‘CHRIST’ sections, except for one or two residues conservation.
The next protein chromatin modification-related protein EAF7-like XP_048006383.1 with less homology but still many highly homologous sections, just one as example:
Query 40 DKVFRSS--------VLHSTQDLFLPFFSNVTWFHAIHVSGTNGT 76
D VFR+S + H+T++ F V + SG N +
Sbjct 406 DLVFRTSDSFENLEPIAHTTENFDNEEFEPVEEMREAQGSGANES 450
And when you see Nature articles title like this one:”SARS-CoV-2 restructures host chromatin architecture”, you might ask WTH (what the hell) is going on here? Have to put this new link to an interview with an incredibly suffering nurse:
Dawn is mentioning a Forkhead protein related possibly to her cancers. The chromatin remodeling proteins do interact with forkheads in order to rearrange DNA strands. That’s why Forkheads do contains DNA binding domains (FOX-DBD) with known motifs, summary of which is accessible at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501956/ . Table 1 of that pub lists the determined structures of these motifs, among others, one of those ‘GTAAACA’. Is it in the Spike? Sure it is (sorry for the increasing irony), right at the position 25091-25097 of the entire SARS-CoV-2 genome with 21563-25384 range covering the Spike (https://www.ncbi.nlm.nih.gov/nuccore/NC_045512). Pdb Data Bank entry at https://www.rcsb.org/fasta/entry/7CBY/display shows how that piece of HUMAN DNA (now in synthetic Spike genome) binds the human Forkhead box protein G1.
A large family of serine incorporator 4 proteins with example XP_045305889.1 contains the very unique cysteine rich section, very homologous to the Spike and very rare among proteins:
Query 1235 CCMTSCCSCLKGCC 1248 Spike
CC + C+C CC
Sbjct 41 CCGPAPCTC---CC 51 serine incorporator 4
or by hand:
CM-TSCCSCLKGCCSCGSCCK Spike
+ SCC C+C CC+
FYQVSCCGPAP--CTC--CCH Serine incorporator 4
Query 356 KRISN 360 Spike
RIS
Sbjct 510 HRIST 514 Serine incorporator 4
extention of the above by hand adding the C-terminal section
Query 356 YAWNRKRISNCV 360 Spike
+ +RIS <<< the highest homology with 'CHRIST' section
Sbjct 510 FRRQCHRISTAR 514 serine incorporator 4
The ‘CHRIST’ section in all Serine Incorporator Protein Families is located at the very C-terminal end and in case of this protein from Leopardus geoffroyi (Geoffroy's cat) (https://www.ncbi.nlm.nih.gov/protein/XP_045305889.1), it actually ends with almost the biblical inter-twinned words ‘CHRISTAR‘=CHRIST-STAR. Also in this case the serine incorporator 4 protein containing the sequence ‘CHRIST’ is connected with SARS-CoV-2^3.
Next WD-40 repeat protein located at https://www.ncbi.nlm.nih.gov/protein/PNY03708.1 . Here its few BLAST alignments with Spike:
Query 1109 FYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPE-----LDSFKEELD-KYFKNHTSP
FY+P+++T +N+ G +G +TV P+ E + ++ L+ +Y +H
Sbjct 733 FYQPEVLTNENSIDFGTTQ--LGGKLDTVKLPVWAENPIDFIHKHRKALESEYVSSHLHE
here the ACE2 receptor bindinding domain:
Query 438 SNNLDSKVGGNYN--YLYR-LFRKSNLKPFERDISTEIYQAGST 478 Spike
SN + G Y +LYR L R+S L+ F D S + GS+ <<IDENTITIES
Sbjct 483 SNETSATTDGVYKCEFLYRYLLRRSALELFMVDRSNFFFDFGSS 526 WD-40
Query 79 FDNPVLP-FNDGVYFAS 94 Spike
FD+PV+P F+ G +++S << IDENTITIES
Sbjct 643 FDDPVIPKFHYGSHYSS 659 WD-40
and one of the highest scored aligned 'CHRIST' section:
Query 615 VNCTEVPVAIHADQLTPTWR 634 Spike
V C + IHA WR
Sbjct 278 VTCHRISTGIHA------WR 291 WD-40 'CHRIST' section
and now the only best conserved 'CHRIST' section in Spike:
Query 354 NRKRISNCVADYSVLYNSASFSTFKC 379 Spike
+RI+ V +YS ++ + +KC
Sbjct 471 TSRRINFIVDNYSNETSATTDGVYKC 496 WD-40
Is there anything in common between WD-40 repeat like proteins with the WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly, and Spike??? Sure there is, the recent research, just published in the most prestigious journal, available at https://www.nature.com/articles/s41467-023-44076-3 ^4. This it the first time when the scientists talk about ‘genetic vaccines’, for a change… Here one sentence from their abstract, quote: “Because this C-terminal residue is the key determinant of SARS-CoV-2 assembly and fusogenicity our work provides a framework for the export of S protein encoded in genetic vaccines for surface display and immune activation“.
One more, this huge one, >5000 resides, its name MIDASIN (could be mid-a-SIN) with ~90% sequence coverage and ~40% IDENTITIES(!!) with Spike. It is s.c. AAA ATPase with vWA domain (i.e. Von Willebrand factor type A domain), involved in ribosome maturation (Translation, ribosomal structure and biogenesis):
Query 737 DCTMYICGDSTECSNLLLQYGSFCTQLNRALTG 769 Spike
D + Y CGDST S+L+ F + L R + G
Sbjct 4956 DSSDYKCGDSTHSSSLM-----FYSNLKRIVMG 4983 Midasin
Query 132 EFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKN
E C F + + N++W RV S F +MD + K+GN+K
Sbjct 1208 ERDLCVASFFVLVERQRNEAW---RARVKSIIEKWCF-------MMDRDDKKGNWKE
Query 1244 LKGCCSCG--SCCKFD-EDDSEP 1263 Spike
LK C+ G K D EDD E
Sbjct 5140 LKRVCTVGVDRVLKLDSEDDQEN 5162 Mid-a-SIN
two Spike sections align with the 'CHRIST' motif in Mid-A-SIN
Query 1001 LQSLQTYVTQQLIRAAEIRA 1020 Spike
+ TYV+Q I + +RA
Sbjct 178 CHRISTYVSQHDIILSPVRA 197 Mid-A-SIN 'CHRIST-1'section
Query 354 NRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVY 396 Spike
+RIS V+ + ++ + K + K++ N+Y
Sbjct 180 FCHRISTYVSQHDIILSPVRADDVKVFCDGIEKISTEIRKNLY 219 Mid-A-SIN
=> the 'KRIS'section of Spike shows the highest homology found by BLAST
And is that Mid-A-SIN with its Von Willebrand factor type A domain somewhat related to covid19?? Of course it is, a big time, here only two citations ^5,^6, out of countless more…
This one is also special, CRISPR/Cas system-associated protein Cas3, taken out of human oral metagenome with sequence in https://www.ncbi.nlm.nih.gov/protein/PIE47861.1. Here just few alignments, including the ‘CHRIST’ section in comparison with Spike:
Query 451 YLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQS 494 Spike RBD
++Y F +N KP DIS I + + N F + S
Sbjct 948 FIYPGFETNNFKPHSYDISELITENQLARIDAQARINNNFAMDS 991 Cas3
Query 134 QFCNDPFLGV-----YYHKNNKS 151 Spike
Q CND GV YHK +KS
Sbjct 762 QLCNDLMQGVIQLHQRYHKLDKS 784 Cas3
and now THREE(!!!) Spike pieces aligned with 'CHRIST' section in Cas3:
Query 365 YSVLYNSASFST-FKCYGVSPTKL-------------NDLCFTNV 395 Spike
Y +L +SAS ST C +S KL N+L + V
Sbjct 46 YQLLKDSASRSTAVSCHRISTRKLTKLVWIVGNKRKFNELGYVAV 90 Cas3
Query 669 GICASYQTQTNSPRRARSVASQSIIAY 695 Spike FURIN site!!!
G+ + YQ +S R+ +V+ I +
Sbjct 41 GLRTVYQLLKDSASRSTAVSCHRISTR 67 Cas3
Query 347 FASVYAWNRKRISNCVADYSVLYNSASFST-FKCYGVSPTKLNDLCF 392
+V Y +L +SAS ST C+ +S KL L +
Sbjct 42 LRTV--------------YQLLKDSASRSTAVSCHRISTRKLTKLVW 74
For this one that’s not even a question to relate it to SARS-CoV-2, this time, to its detection^7,^8…
And few more examples:
DNA endonuclease rbbp8 KAI8505736.1
Query 1069 PAQEKNFTTAPAICHDGKA 1086 Spike
PA + PA CH +
Sbjct 43 PAADGAEPDTPAPCHRIST 60 rbb8
Toll/interleukin-1 receptor domain-containing protein [Oscillospiraceae bacterium] MBR4036625.1
Query 229 LPIGINITRFQTLLALHRSYL 246 Spike
L +GI F + HR
Sbjct 538 LVMGIVENPFNWYVDCHRIST 555 Toll receptor
Pseudomonas phosphoenolpyruvate--protein phosphotransferase (PtsA)
Query 10 LVSSQCVNLTTRT-QLPPAYTNSFTRGVYYP 39
L ++QC ++T LP A ++P
Sbjct 805 LDAAQCHRISTDLLNLPSAAAVRQACHQHWP 835
A special addition, because of its importance in governmental interests (DOE, LBNL, Los Alamos National Laboratory), it is a fungal protein from HET-R family. A review from 2000^9 describes that cell fusions in fungi can lead to cells with different nuclear types forming s.c. heterokaryons, genetically controlled by specific loci termed het loci (for heterokaryon incompatibility). From that 2000 abstract: “Heterokaryotic cells formed between individuals of unlike het genotypes undergo a characteristic cell death reaction or else are severely inhibited in their growth.” Here some of the alignment of HET-R protein with Spike (this time in Sbjct line):
Query 79 PVRVVVYS 86 HET-R
P RVVV S
Sbjct 507 PYRVVVLS 514 SARS-CoV-2 Spike
Query 640 DVSGLNS 646 HET-R
D+SG+N+
Sbjct 1168 DISGINA 1174 SARS-CoV-2 Spike
Query 259 QIFSGSSDGTLRVWDVQSGTCRHTISGHGDNVNCVA 294 HET-R
++F+ + ++ W+ R IS NCVA
Sbjct 340 EVFNATRFASVYAWN------RKRIS------NCVA 363 SARS-CoV-2 Spike
Query 167 VYSPKGDQVASGCADSSVRLWNVASG HET-R
VY+ ++++ AD SV L+N AS
Sbjct 349 VYAWNRKRISNCVADYSV-LYNSASF SARS-CoV-2 Spike
Query 391 YDGTMRLWDVDTGTCHRISTGHTS 414 HET-R
YD D + HTS
Sbjct 1138 YDPLQPELDSFKEELDKYFKNHTS 1161 SARS-CoV-2 Spike
and last with manual adition:
SPRRARSVASQ >>SARS-CoV-2 Spike Furin Site
SP+ VAS
Query 168 VYSPKGDQVASGCADSSVRLWNVASGECSHIF HET-R
VY+ ++++ AD SV L+N AS +
Sbjct 350 VYAWNRKRISNCVADYSV-LYNSASFSTFKCY SARS-CoV-2 Spike
There are so many, many more proteins with the above features. But that above implies to me already, that Spike was build from relevant proteins which contain the amino acids sequence, that short peptide ‘CHRIST’, which during the incorporation was overwritten with different amino acids (code) in highly homologous sections. All those proteins carrying the word related to CHRISTmas are also closely related with specific SARS-CoV-2 characteristics. It is as if one can take all the proteins containing the special sequence ‘CHRIST’ (without even concentrating on species), and their functions will be related to Spike, while not having that sequence anymore in Spike.
On the other hand that highest homology tripeptide ‘RIS’ from the last BLAST output above, in the Spike and the ‘Serine Incorporator 4’
has its short homolog in protein called luciferase (NIH data location at https://www.ncbi.nlm.nih.gov/protein/UUA44467.1 ). BLAST finds one hit with the Spike ‘RIS’ section, the second was found by human eyes:
Query 386 QRGELCV 392 Luciferase
GVNQRGELCVRGPM
+R CV
WNRKRISNCVADYS
Sbjct 356 KRISNCV 362 Spike
now by hand, a different part of Luciferase overlaps better with Spike:
GLNTNHRIVVCS Luciferase
++I C
YAWNRKRISNCV Spike2020
or when adding gaps:
GLNTNH-RIVVCS Luciferase
N+ RI C
YAW-NRKRISNCV Spike2020
We know SARS-CoV-2, its Spike in particular, was designed over a period of many years, ending with countless patents. Current bioinformatics search for anything related to Spike, ends up with many, many thousands of Spike closely related ‘variants’, to a level where in fact one can’t find anything, but the Spike. A digital bio-invasion, in my opinion. If the ‘Spike origin idea’ presented here, has nevertheless some meaning in reality, if it is indeed true (it looks to me like it is), then imagine the amount of HATE that ‘somebody’ (who pays for all this ‘modern science’) must have against the ORIGINAL CREATOR, GOD. That hate must be immense, based on incredible jealousy, resulting in overwriting the original genetic code, with the one, which does not carry the word ‘CHRIST’ any more.
Dr. Fauci (Jesuit) and his connection with this special day was mentioned exactly a year ago, in a post at, with quite few non-existing links any more:
Thank you for your attention.
Literature:
David G Alleva et al. “Development of an IgG-Fc fusion COVID-19 subunit vaccine, AKS-452“ Vaccine 2021 Oct 29;39(45):6601-6613. https://pubmed.ncbi.nlm.nih.gov/34642088/
Shaofen Xu et al. “The Emerging Role of the Serine Incorporator Protein Family in Regulating Viral Infection“ Front Cell Dev Biol. 2022; 10: 856468. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010877/
Debajit Dey et al. “A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs” Nature Communications | (2023)14:8358 https://www.nature.com/articles/s41467-023-44076-3
Yoshihiro Fujimura # 1 , Linda Z Holland “COVID-19 microthrombosis: unusually large VWF multimers are a platform for activation of the alternative complement pathway under cytokine storm“ Int J Hematol. 2022 Apr;115(4):457-469.https://pubmed.ncbi.nlm.nih.gov/35316498/
Kan Li et al. “SARS-CoV-2 Spike protein promotes vWF secretion and thrombosis via endothelial cytoskeleton-associated protein 4 (CKAP4)“ Signal Transduction and Targeted Therapy volume 7, Article number: 332 (2022). https://www.nature.com/articles/s41392-022-01183-9
Pallavi Deol et al. “CRISPR use in diagnosis and therapy for COVID-19“ Methods in Microbiology. 2022; 50: 123–150. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073596/
Kazuto Yoshimi e tal. “CRISPR-Cas3-based diagnostics for SARS-CoV-2 and influenza virus“ iScience. 2022 Feb 18; 25(2): 103830. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801231/
Sven J. Saupe “Molecular Genetics of Heterokaryon Incompatibility in Filamentous Ascomycetes” Microbiol Mol Biol Rev. 2000 Sep; 64(3): 489–502. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC99001/
'Christ' as in english, swedish, french, zulu. What about the other languages? 😊
Merry Christmas!